1.1.1 Diagnosis established with spirometry
1.1.2 Chest x-ray not diagnostic
1.1.3.1 Catherine Beigelman-Aubry, André Capderou, Philippe A. Grenier, Christian Straus, Marie-Hélène Becquemin, Thomas Similowski, and Marc Zelter Mild Intermittent Asthma: CT Assessment of Bronchial Cross-sectional Area and Lung Attenuation at Controlled Lung Volume Radiology April 2002 223:181-187
1.1.3.2 McKenzie SA. Difficult asthma in children. Eur Respir Review 2000;60:18 -22
1.1.3.3 Marchac, Valentine, Emond, Sophie, Mamou-Mani, Tania, Le Bihan-Benjamin, Christine, le Bourgeois, Muriel, de Blic, Jacques, Scheinmann, Pierre, Brunelle, Francis Thoracic CT in Pediatric Patients with Difficult-to-Treat Asthma Am. J. Roentgenol. 2002 179: 1245-1252
1.1.3.4 Phillips, CD, Platts-Mills, TA Chronic sinusitis: relationship between CT findings and clinical history of asthma, allergy, eosinophilia, and infection Am. J. Roentgenol. 1995 164: 185-187
1.2.1.1.1 CTA or MRA of the chest and abdomen are the preferred examinations, routine CT or MR are acceptable especially if dissection is not the only diagnosis under consideration. This is a true emergency with mortality increasing about 1% per hour. Michelle A. McMahon and Christopher A. Squirrell Multidetector CT of Aortic Dissection: A Pictorial Review Radiographics March 2010 30:445-460
1.2.1.2.1 Absent distal pulses
1.2.1.2.2 Acute onset of severe chest, upper back, or abdominal pain.
1.2.1.2.3 Pain with abnormal appearance of aorta on prior imaging
1.2.1.2.4 Prior Aneurysm Repair
1.2.1.2.5 Unequal blood pressure in arms
1.2.1.3.1 ACR Appropriateness Criteria® Acute Chest Pain-Suspected Aortic Dissection 2008
1.2.1.3.2 A. Khan and Chandra K. Nair Clinical, Diagnostic, and Management Perspectives of Aortic Dissection Chest July 2002 122:311-328;
1.2.1.3.3 Kersting-Sommerhoff, BA, Sechtem, UP, Fisher, MR, Higgins, CB MR imaging of congenital anomalies of the aortic arch Am. J. Roentgenol. 1987 149 9-13
1.2.1.3.4 Paul J. Arpasi, Kostaki G. Bis, Anil N. Shetty, Richard D. White, and Orlando P. Simonetti MR Angiography of the Thoracic Aorta with an Electrocardiographically Triggered Breath-Hold Contrast-enhanced Sequence RadioGraphics 2000 20: 107-120.
1.2.1.3.5 Prince MR. Gadolinium-enhanced MR aortography. Radiology 1994; 191:155-164.
1.2.1.3.6 Roche, Kevin J., Rivera, Rafael, Argilla, Michael, Fefferman, Nancy R., Pinkney, Lynne P., Rusinek, Henry, Genieser, Nancy B. Assessment of Vasculature Using Combined MRI and MR Angiography Am. J. Roentgenol. 2004 182: 861-866
1.2.1.3.7 Patel, Pawan D., Arora, Rohit R. Pathophysiology, diagnosis, and management of aortic dissection Therapeutic Advances in Cardiovascular Disease 2008 2: 439-468
1.2.1.3.8 G. Sutsch et al, Predictability of aortic dissection as a function of aortic diameter Eur. Heart J., Jan 1991; 12: 1247 – 1256.
1.2.1.3.9 Robert G. Hayter, James T. Rhea, Andrew Small, Faranak S. Tafazoli, and Robert A. Novelline Suspected Aortic Dissection and Other Aortic Disorders: Multi-Detector Row CT in 373 Cases in the Emergency Setting Radiology 2006 238: 841-852
1.2.2.1.1 Cough
1.2.2.1.2 Dyspnea, acute onset
1.2.2.1.3 Hemoptysis
1.2.2.1.4 Tachypnea
1.2.2.1.5 Pleuritic chest pain
1.2.2.2.1 Age over 65
1.2.2.2.2 Immobiliztion, Recent or Current
1.2.2.2.3 Known DVT or Pulmonary Embolus
1.2.2.2.4 Known Malignancy
1.2.2.2.5 Excess Estrogen State
1.2.2.2.6 Positive D-Dimer
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632
Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
1.3.1 Negative prior work up for ACE therapy
1.3.2 Negative prior work up for Asthma
1.3.3 Negative prior work up for GERD
1.3.4 Negative prior work up for Upper AirwayCough Syndrome (UACS or PND)
1.3.5.1 Current Medical Diagnosis & Treatment 2007 Stephen J. McPhee, Maxine A. Papadakis, and Lawrence M. Tierney, Jr., Eds. Ralph Gonzales, Roni Zeiger, Online Eds. Cough Ralph Gonzales, MD, MSPH
1.4.1 Known Malignancy (Lung or Mediastinum)
Thurer, RL,, Evaluation of Mediastinal Masses in UpToDate Online Accessed 7/5/07 Sabiston Textbook of Surgery Copyright © 2004 Elsevier. p. 1739
1.5.1.1 Pend for Physician Review as a CTA Chest (71275) is the preferred study
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632
Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
Gonzales Ralph, Nadler Paul L, “Chapter 2. Common Symptoms” (Chapter). McPhee SJ, Papadakis MA, Tierney LM, Jr.: CURRENT Medical Diagnosis & Treatment 2009: http://www.accessmedicine.com/content.aspx?aID=79
1.7.1.1 CT neck should be performed before a CT of the chest is approved for hoarseness. According to the ACR Guidelines the CT of the neck will include structures in the upper chest, to about the level of the carina, that might contribute to hoarseness.
1.7.1.2.1 ACR PRACTICE GUIDELINE FOR THE PERFORMANCE OF COMPUTED TOMOGRAPHY (CT) OF THE EXTRACRANIAL HEAD AND NECK IN ADULTS AND CHILDREN accessed at www.acr.org/SecondaryMainMenuCategories/quality_safety/guidelines/dx/head-neck/ct_head_neck.aspx 5/11/11
1.7.2 Laryngoscopy nondiagnostic
1.7.3 Persists for > ten days
1.7.4.1 Richardson BE et al. Clinical evaluation of vocal fold paralysis. Otolaryngol Clin North Am. 2004 Feb;37(1):45-58.
1.7.4.2 Case report: Collapse, hoarseness of the voice and swelling and bruising of the neck: an unusual presentation of thoracic aortic dissection W Al-Hity, M J Playforth Emerg Med J 2001;18:508-509
1.7.4.3 New Clinical Guideline for Hoarseness Offers Assessment and Treatment Advice Mike Mitka JAMA. 2009;302(18):1954-1956
1.8.1 See Aortic dissection suspected
1.8.2.1.1 Cough
1.8.2.1.2 Dyspnea, acute onset
1.8.2.1.3 Hemoptysis
1.8.2.1.4 Tachypnea
1.8.2.1.5 Pleuritic chest pain
1.8.2.2.1 Age over 65
1.8.2.2.2 Immobiliztion, Recent or Current
1.8.2.2.3 Known DVT or Pulmonary Embolus
1.8.2.2.4 Known Malignancy
1.8.2.2.5 Excess Estrogen State
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632 Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
1.9.1.1.1 Cough
1.9.1.1.2 Dyspnea, acute onset
1.9.1.1.3 Hemoptysis
1.9.1.1.4 Tachypnea
1.9.1.1.5 Pleuritic chest pain
1.9.1.2.1 Age over 65
1.9.1.2.2 Immobiliztion, Recent or Current
1.9.1.2.3 Known DVT or Pulmonary Embolus
1.9.1.2.4 Known Malignancy
1.9.1.2.5 Excess Estrogen State
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632
Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
1.10.1.1.1 Cough
1.10.1.1.2 Dyspnea, acute onset
1.10.1.1.3 Hemoptysis
1.10.1.1.4 Tachypnea
1.10.1.1.5 Pleuritic chest pain
1.10.1.2.1 Age over 65
1.10.1.2.2 Immobiliztion, Recent or Current
1.10.1.2.3 Known DVT or Pulmonary Embolus
1.10.1.2.4 Known Malignancy
1.10.1.2.5 Excess Estrogen State
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632
Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
1.11 Weight loss (involuntary) of more than 5% body weight over 6 months
2.1.1 Aneurysm on prior examination
2.1.2 Aortic Arch abnormal on CXR
2.1.3 Arch or Descending Aorta > 3.5 cm diameter on CXR
2.1.4 Ascending Aorta > 4.5cm cm diameter on CXR
2.1.5 Marfan’s, Turner’s or Ehlers-Danlos Syndrome
Elefteriades John A, Olin Jeffrey W, Halperin Jonathan L, “Chapter 105. Diseases of the Aorta” (Chapter). Fuster V, O’Rourke RA, Walsh RA, Poole-Wilson P, Eds. King SB, Roberts R, Nash IS, Prystowsky EN, Assoc. Eds.: Hurst’s The Heart, 12th Edition: http://www.accessmedicine.com/content.aspx?aID=3075150. Eli Atar, Alexander Belenky, Menashe Hadad, Ehud Ranany, Shlomo Baytner, and Gil N. Bachar MR Angiography for Abdominal and Thoracic Aortic Aneurysms: Assessment Before Endovascular Repair in Patients with Impaired Renal Function Am. J. Roentgenol., Feb 2006; 186: 386 – 393. Eric M. Isselbacher Thoracic and Abdominal Aortic Aneurysms Circulation, Feb 2005; 111: 816 – 828. Christian Olsson, Stefan Thelin, Elisabeth Ståhle, Anders Ekbom, and Fredrik Granath Thoracic Aortic Aneurysm and Dissection: Increasing Prevalence and Improved Outcomes Reported in a Nationwide Population-Based Study of More Than 14 000 Cases From 1987 to 2002 Circulation, Dec 2006; 114: 2611 – 2618. S. Iliceo, G. Ettorre, et al Diagnosis of aneurysm of the thoracic aorta. Comparison between two non invasive techniques: two-dimensional echocardiography and computed tomography Eur. Heart J., Jul 1984; 5: 545 – 555.
2.2.1.1 CTA or MRA of the chest and abdomen are the preferred examinations, routine CT or MR are acceptable especially if dissection is not the only diagnosis under consideration. This is a true emergency with mortality increasing about 1% per hour. Michelle A. McMahon and Christopher A. Squirrell Multidetector CT of Aortic Dissection: A Pictorial Review Radiographics March 2010 30:445-460
2.2.2.1 Absent distal pulses
2.2.2.2 Acute onset of severe chest, upper back, or abdominal pain
2.2.2.3 Pain with abnormal appearance of aorta on prior imaging
2.2.2.4 Prior Aneurysm Repair
2.2.2.5 Unequal blood pressure in arms
ACR Appropriateness Criteria® Acute Chest Pain-Suspected Aortic Dissection 2008
Khan and Chandra K. Nair Clinical, Diagnostic, and Management Perspectives of Aortic Dissection Chest July 2002 122:311-328; Kersting-Sommerhoff, BA, Sechtem, UP, Fisher, MR, Higgins, CB MR imaging of congenital anomalies of the aortic arch Am. J. Roentgenol. 1987 149 9-13 Paul J. Arpasi, Kostaki G. Bis, Anil N. Shetty, Richard D. White, and Orlando P. Simonetti MR Angiography of the Thoracic Aorta with an Electrocardiographically Triggered Breath-Hold Contrast-enhanced Sequence RadioGraphics 2000 20: 107-120. Prince MR. Gadolinium-enhanced MR aortography. Radiology 1994; 191:155-164.Roche, Kevin J., Rivera, Rafael, Argilla, Michael, Fefferman, Nancy R., Pinkney, Lynne P., Rusinek, Henry, Genieser, Nancy B. Assessment of Vasculature Using Combined MRI and MR Angiography Am. J. Roentgenol. 2004 182: 861-866 Patel, Pawan D., Arora, Rohit R. Pathophysiology, diagnosis, and management of aortic dissection Therapeutic Advances in Cardiovascular Disease 2008 2: 439-468 G. Sutsch et al, Predictability of aortic dissection as a function of aortic diameter Eur. Heart J., Jan 1991; 12: 1247 – 1256.
2.3.1 Diagnosis established with spirometry
2.3.2 Chest x-ray not diagnostic
Catherine Beigelman-Aubry, André Capderou, Philippe A. Grenier, Christian Straus, Marie-Hélène Becquemin, Thomas Similowski, and Marc Zelter Mild Intermittent Asthma: CT Assessment of Bronchial Cross-sectional Area and Lung Attenuation at Controlled Lung Volume Radiology April 2002 223:181-187;
McKenzie SA. Difficult asthma in children. Eur Respir Review 2000;60:18 -22
Marchac, Valentine, Emond, Sophie, Mamou-Mani, Tania, Le Bihan-Benjamin, Christine, le Bourgeois, Muriel, de Blic, Jacques, Scheinmann, Pierre, Brunelle, Francis Thoracic CT in Pediatric Patients with Difficult-to-Treat Asthma Am. J. Roentgenol. 2002 179: 1245-1252
2.4.1 Note Plexopathy refers to an abnormality of the complex of nerve roots exiting the spine and organizing into the nerves serving the arm, trunk or legs. Symptoms may include burning, tingling, or numbness in a circumferential or dermatomal distribution. The symptoms may radiate to the hand or remain localized in the neck.
2.4.2.1.1.1 Aliya Qayyum, A. David MacVicar, Anwar R. Padhani, Patrick Revell, and Janet E. S. Husband Symptomatic Brachial Plexopathy following Treatment for Breast Cancer: Utility of MR Imaging with Surface-Coil Techniques Radiology March 2000 214:837-842
2.4.2.1.2.1 Bowen, BC, Verma, A, Brandon, AH, Fiedler, JA Radiation-induced brachial plexopathy: MR and clinical findings AJNR Am J Neuroradiol 1996 17: 1932-1936
2.4.2.1.3 Palpable mass in neck or shoulder area
2.4.2.1.4 Truama, including at birth
2.4.2.2.1 Numbness
2.4.2.2.2 Paresthesias
2.4.2.2.3 Radiating pain
2.4.2.2.4 Weakness
ACR Appropriateness Criteria Plexopathy p10 Accessed 12/28/08 Aliya Qayyum, A. David MacVicar, Anwar R. Padhani, Patrick Revell, and Janet E. S. Husband Symptomatic Brachial Plexopathy following Treatment for Breast Cancer: Utility of MR Imaging with Surface-Coil Techniques Radiology 2000 214: 837-842. BC Bowen, A Verma, AH Brandon, and JA Fiedler Radiation-induced brachial plexopathy: MR and clinical findings AJNR Am. J. Neuroradiol., Nov 1996; 17: 1932 – 1936. Neurosurgical Focus Posted 04/02/2007 Accessed 1/4/09 @ http://www.medscape.com/viewarticle/553963_1
Bowen B, Seidenwurm DJ, Davis P, et al, Expert Panel on Neurologic Imaging, American College of Radiology, Appropriateness Criteria, Plexopathy, accessed at http://www.acr.org/SecondaryMainMenuCategories/quality_safety/app_criteria/pdf/ExpertPanelonNeurologicImaging/PlexopathyDoc12.asp 12/28/08 Devin K. Binder, M.D., Ph.D.; Justin S. Smith, M.D., Ph.D.; Nicholas M. Barbaro, M.D Primary Brachial Plexus Tumors: Imaging, Surgical, and Pathological Findings in 25 Patients Neurosurgical Focus Medscape Radiology accessed 12/28/08 Edward Fathers, David Thrush, Susan M Huson, and Andrew Norman Radiation-induced brachial plexopathy in women treated for carcinoma of the breast Clinical Rehabilitation, Feb 2002; 16: 160 – 165. Neoplastic Brachial Plexopathy Author: Mark A Wren, MD, MPH, Medical Director, Department of Physical Medicine and Rehabilitation, HealthSouth Rehabilitation Hospital of Texarkana eMedicine Specialties > Physical Medicine and Rehabilitation > Plexopathy Updated: Jan 19, 2010 Accesed 3/15/10 Vincent J. Miele, M.D.; John A. Norwig, A.T.C.; Julian E. Bailes, M.D. Sideline and Ringside Evaluation for Brain and Spinal Injuries Walker, AT, Chaloupka, JC, de Lotbiniere, AC, Wolfe, SW, Goldman, R, Kier, EL Detection of nerve rootlet avulsion on CT myelography in patients with birth palsy and brachial plexus injury after trauma Am. J. Roentgenol. 1996 167: 1283-1287 T. Yoshikawa, N. Hayashi, S. Yamamoto, Y. Tajiri, N. Yoshioka, T. Masumoto, H. Mori, O. Abe, S. Aoki, and K. Ohtomo Brachial Plexus Injury: Clinical Manifestations, Conventional Imaging Findings, and the Latest Imaging Techniques RadioGraphics, October 1, 2006; 26(suppl_1): S133 – S143.
TAVAKKOLIZADEH, A. SAIFUDDIN, and R. BIRCH Imaging of Adult Brachial Plexus Traction Injuries J Hand Surg Eur Vol., June 1, 2001; 26(3): 183 – 191
2.5 Boerhaave’ Syndrome See Esophageal Rupture
2.6.1 Cough
2.6.2 Production of mucopurulent sputum
2.6.3 Hemoptysis
2.6.4 Dyspnea
2.6.5 Wheezing or crackles
2.6.6 Pleuritic chest pain
2.6.7 Digital clubbing
2.6.8 Bronchiectasis on prior CXR
2.6.9 History of cystic fibrosis
2.6.10 Primary ciliary dyskinesia
2.6.11 Known alpha 1-antitrypsin deficiency
2.6.12.1 Chronic moist/productive cough
2.6.12.2 Asthma that does not respond to treatment
2.6.12.3 Asthma that does not respond to treatment
2.6.12.4 Recurrent pneumonia
2.6.12.5 Unexplained hemoptysis
2.6.12.6 Positive sputum culture
Kerby Gwendolyn S, Deterding Robin R, Balasubramaniam Vivek, Sagel Scott D, Cavanaugh Keith L, Federico Monica J, “Chapter 18. Respiratory Tract & Mediastinum” (Chapter). Hay WW, Jr., Levin MJ, Sondheimer JM, Deterding RR: CURRENT Diagnosis & Treatment: Pediatrics, 19th Edition: http://www.accessmedicine.com/content.aspx?aID=3402130. Dodd, Jonathan D., Souza, Carolina A., Muller, Nestor L. Conventional High-Resolution CT Versus Helical High-Resolution MDCT in the Detection of Bronchiectasis Am. J. Roentgenol. 2006 187: 414-420
2.7.1.1 FEV1, FVC, and the FEV1/FVC (FEV1% ratio) are reduced
2.7.2 Distant breath sounds
2.7.3 Known with worsening symptoms
Prendergast Thomas J, Ruoss Stephen J, “Chapter 9. Pulmonary Disease” (Chapter). McPhee SJ, Ganong WF: Pathophysiology of Disease, 5th Edition: http://www.accessmedicine.com/content.aspx?aID=2094128. accessed 1/16/09
2.8.1.1 Instrumentation of any kind
2.8.1.2 Wretching or vomiting
UptoDate 18.2: George Triadafilopoulos, MD Boerhaave’s syndrome: Effort rupture of the esophagus
Perforation of the esophagus: correlation of site and cause with plain film findings. Han SY; McElvein RB; Aldrete JS; Tishler JM AJR Am J Roentgenol 1985 Sep;145(3):537-40. Esophageal injuries: spectrum of multidetector row CT findings. de Lutio di Castelguidone E; Merola S; Pinto A; Raissaki M; Gagliardi N; Romano L Eur J Radiol. 2006 Sep;59(3):344-8.
2.9.1 Known or suspected based on prior imaging or abnormal pulmonary function test
2.9.2 Persistent nonproductive cough
2.9.3 Hemoptysis
2.9.4.1 Sarcoidosis
2.9.4.2 Collagen vascular diseases (scleroderma, dermatomyositis, SLE/lupus, rheumatoid arthritis, polymyositis, sjogren syndrome, mixed connective tissue disease)
2.9.4.3 Tuberous sclerosis
2.9.4.4 Wegener’s granulomatosis
2.9.4.5 Bronchiolitis obliterns organizing pneumonia (BOOP)
2.9.4.6 Occupational exposure (asbestosis, silicosis)
2.9.5 Drug related diseases
2.9.6 Interstitial infiltrate on a recent chest x-ray with or without abnormal PFT’s
2.9.7 Interstitial lung disease suspected in children, with or without abnormal PFT’s
2.9.8.1 Bourke, S J; Interstitial lung disease: progress and problems; Postgrad Med J 2006 82: 494-499
2.9.8.2 Du Bois, R M Fortnightly Review: Diffuse lung disease: an approach to management BMJ 1994;309:175
2.10.1 Recurrent in the same location
2.10.2 Unresponsive to treatment.
2.11.1 Pend for Physician Review as a CTA Chest (71275) is the preferred study
Massimo Pistolesi Pulmonary CT Angiography in Patients Suspected of Having Pulmonary Embolism: Case Finding or Screening Procedure? Radiology August 2010 256:334-337; Mark D. Mamlouk, Eric vanSonnenberg, Rishi Gosalia, David Drachman, Daniel Gridley, Jesus G. Zamora, Giovanna Casola, and Sanford Ornstein Pulmonary Embolism at CT Angiography: Implications for Appropriateness, Cost, and Radiation Exposure in 2003 Patients Radiology August 2010 256:625-632
Patel S, Kazerooni EA. Helical CT for the evaluation of acute pulmonary embolism. AJR Am J Roentgenol 2005;185(1):135–149 Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006;354(22):2317–2327 Perrier A, Roy PM, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005;352(17):1760–1768
2.12.1 Bilateral Hilar adenopathy
2.12.2 Uveitis
2.12.3 Elevated serum calcium (hypercalcemia)
2.12.4 Optic Neuritis
2.12.5 Skin rash
Baughman RP, Lower EE. Chapter 329. Sarcoidosis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison’s Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012. http://www.accessmedicine.com/content.aspx?aID=9138725. Accessed October 18, 2012 Sarcoidosis: Clinical Presentation, Immunopathogenesis, and Therapeutics Michael C. Iannuzzi, Joseph R. Fontana JAMA. 2012;305(4):391-399.Sarcoidosis: correlation of extent of disease at CT with clinical, functional, and radiographic findings. Müller NL, Mawson JB, Mathieson JR, Abboud R, Ostrow DN, Champion P Radiology. 1989;171(3):613. Pulmonary sarcoidosis. Baughman RP Clin Chest Med. 2004;25(3):521 Radiologic manifestations of sarcoidosis in various organs. Koyama T, Ueda H, Togashi K, Umeoka S, Kataoka M, Nagai S Radiographics. 2004;24(1):87.
2.13.1.1 History of at least 20 pack years (daily number of packs smoked multiplied by the number of years smoked)
2.13.1.2 Currently smoking or smoked within the last 15 years
2.13.1.3 Aged between 50 and 80 years
2.13.2.1 History of at least 20 pack years (daily number of packs smoked multiplied by the number of years smoked)
2.13.2.2Currently smoking, or smoked within the last 15 years
2.13.2.3 Aged between 50 and 77 years
Draft Recommendation Statement USPTF Accesses 10/28/2013 at
http://www.uspreventiveservicestaskforce.org/uspstf13/lungcan/lungcandraftrec.htm http://pubs.rsna.org/doi/pdf/10.1148/rg.2015150079
US Preventive Services Task Force Lung Cancer Screening Recommendations, March 9, 2021
https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
2.14.1 facial or neck swelling,
2.14.2 bilateral upper extremity swelling,
2.14.3 dyspnea,
2.14.4 headache,
2.14.5 cough
2.15.1 Known Malignancy (Lung or Mediastinum)
2.15.2.1 Thurer, RL,, Evaluation of Mediastinal Masses in UpToDate Online Accessed 7/5/07
2.15.2.2 Sabiston Textbook of Surgery Copyright © 2004 Elsevier. p. 1739
2.16.1 Anterior mediastinal mass
2.16.2 Myesthenia gravis
2.16.3 Phrenic nerve palsy,
2.16.4 Superior vena cava obstruction
2.16.5 Ptosis or drooping of the eyelid
2.16.6 Diplopia or double vision
2.16.7 Nasal speech
2.16.8 Difficulty chewing or swallowing
2.16.9 Facial paresis
2.16.10 Proximal limb weakness
2.16.11 Chest pain
2.16.12 Dysphagia
2.16.13 Hoarseness
2.16.15.1 Pure red cell aplasia
2.16.15.2 Hypogammaglbulinemia
2.16.15.3 Pure white cell aplasia
2.16.15.4 Multi organ autoimmunity
Sabiston Textbook of Surgery, 17th Edition (2004) Townsend et al, eds; p1746
NCCN Practice Guidelines in Oncology – v.2.2009 Thymic Malignancies Maher MM, Shephard JA. Imaging of thymoma. Semin Thorac Cardiovasc Surg 2005;17:12-19 Lewis JE, Wick MR, Scheithauer BW, Bernatz PE, Taylor WF .Thymoma: A clinicopathologic review. Cancer. 1987;60(11):2727.
2.17.1 Hempotysis
2.17.2 Respiratory distress
2.17.3 Pneumothorax
2.17.4 Acute chest pain
2.17.5 Rales or crackles
2.17.6 Bronchiectasis
2.17.7 Recurrent respiratory infections
2.18.1.1. Decreased serum sodium
2.18.2 Hypercalcemia
2.18.3 Carcinoid syndrome
2.18.4 Glomerulonephritis
2.18.5 Thrombophlebitis
2.19.1.2 Urine culture not diagnostic
2.19.1.3 Tuberculin skin test
2.19.1.4 HIV antibody assay and HIV viral load for patients at high risk
2.19.1.5 Negative chest x-ray
Koelsch TL, Chung JH, Lynch DA. Clin Chest Med. 2015 Jun;36(2):269-82, ix. doi: 10.1016/j.ccm.2015.02.009. Epub 2015 Apr 1.
High-resolution CT of interstitial lung disease: a continuous evolution. Walsh SL, Hansell DM.
Semin Respir Crit Care Med. 2014 Feb;35(1):129-44. doi: 10.1055/s-0033-1363458. Epub 2014 Jan 30.
Scoring of chest CT in children with cystic fibrosis: state of the art. Calder AD, Bush A, Brody AS, Owens CM.
Pediatr Radiol. 2014 Dec;44(12):1496-506. doi: 10.1007/s00247-013-2867-y. Epub 2014 Aug 28.
Bronchiectasis: new approaches to diagnosis and management. Feldman C. Clin Chest Med. 2011 Sep;32(3):535-46. doi: 10.1016/j.ccm.2011.05.002. An official American Thoracic Society/American College of Chest Physicians policy statement: the Choosing Wisely top five list in adult pulmonary medicine. Wiener RS, Ouellette DR, Diamond E, Fan VS, Maurer JR, Mularski RA, Peters JI, Halpern SD; American Thoracic Society; American College of Chest Physicians. Chest. 2014 Jun;145(6):1383-91. doi: 10.1378/chest.14-0670.
3.1.1 Note: A complex CT exam is often called for, including analysis of function by imaging once at inspiration and once at expiration.
Kyprianou Andreas, Feinsilver Steven, “CONCISE REVIEW: Diaphragmatic Dysfunction and Its Evaluation” (Update). Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J: Harrison’s Principles of Internal Medicine, 17th Edition: http://www.accessmedicine.com/updatesContent.aspx?aid=395735
3.2 Pleural fluid on prior imaging or physical examination
3.3.1 facial or neck swelling
3.3.2 bilateral upper extremity swelling
3.3.3 dyspnea
3.3.4 headache
3.3.5 cough
3.4.1 Aortic dissection suspected
Robert G. Hayter, James T. Rhea, Andrew Small, Faranak S. Tafazoli, and Robert A. Novelline Suspected Aortic Dissection and Other Aortic Disorders: Multi-Detector Row CT in 373 Cases in the Emergency Setting Radiology 2006 238: 841-852 Louise A. Prince, Gary A. Johnson in Tintinalli’s Emergency Medicine:A Comprehensive Study Guide, 6th Edition Judith E. Tintinalli, MD, MS, Gabor D. Kelen, MD, J. Stephan Stapczynski, MD, O. John Ma, MD and David M. Cline, MD Eds. The American College of Emergency Physicians> Section 7: Cardiovascular Disease > Chapter 58. Aortic Dissection and Aneurysms
Sabiston Textbook of Surgery, 17th Edition (2004) Townsend et al, eds; pp1907 – 1913
3.5 Vocal cord paralysis, unilateral
4.1 Abnormal or dilated aorta on CXR or abdominal US
4.2.1 Any atalectasis persisting for > 2 days by CXR
4.2.2 Whole segment, lobe or lung
4.3 Bleb, on prior imaging study
4.4.1 Change in clinical condition
4.5 Cavitation on prior imaging
4.6.1 Note: A complex CT exam is often called for, including analysis of function by imaging once at inspiration and once at expiration
4.6.2.1 Kyprianou Andreas, Feinsilver Steven, “CONCISE REVIEW: Diaphragmatic Dysfunction and Its Evaluation” (Update). Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J: Harrison’s Principles of Internal Medicine, 17th Edition: http://www.accessmedicine.com/updatesContent.aspx?aid=395735
4.7 DVT by sonography
4.8.1 3, 6, 12 month follow-up after initial discovery, then annually for two years
Chang Min Park, Jin Mo Goo, Hyun Ju Lee, Chang Hyun Lee, Eun Ju Chun, and Jung-Gi Im Nodular Ground-Glass Opacity at Thin-Section CT: Histologic Correlation and Evaluation of Change at Follow-up RadioGraphics 2007 27: 391-408. :The popularization of computed tomography (CT) in clinical practiceand the introduction of mass screening for early lung cancerwith the use of CT have increased the frequency of findingsof subtle nodules or nodular ground-glass opacity. Nodular ground-glassopacity may be observed in malignancies such as bronchioloalveolarcarcinoma and adenocarcinoma, as well as in their putative precursors,such as atypical adenomatous hyperplasia. Nodular ground-glassopacity also may be seen in the presence of benign conditions,including focal interstitial fibrosis, inflammation, and hemorrhage.The persistence of nodular ground-glass opacity over time maybe strongly suggestive of an early-stage malignancy, especiallyif the lesion increases in size or includes a solid componentthat increases in its extent. Persistent nodular ground-glassopacity also may remain stable in size but show increased attenuation.The more extensive the solid portions of the lesion, the higherthe probability of malignancy and the poorer the prognosis.An awareness of the clinical setting, in addition to familiaritywith the thin-section CT features of nodular ground-glass opacityat initial and follow-up imaging over several months, can helpidentify malignancy and achieve an accurate diagnosis. A meticulousevaluation of those CT features, and their correlation withspecific histopathologic characteristics, also may enable amore accurate prognosis in cases of neoplastic disease. et al reported that the margin characteristics and thesizes of foci of nodular ground-glass opacity were not helpfulfor differentiating between benign and malignant lesions. Instead,they identified benign lesions on the basis of the apparentresolution of nodular ground-glass opacity at short-term follow-upCT; benign lesions, except focal interstitial fibrosis, resolvedpartially or completely within 3 months after initial CT.Benign lesions that are due to inflammation, focal hemorrhage,or edema might resolve spontaneously or after appropriate therapywith antibiotics or steroids.
Li F, Sone S, Abe H, MacMahon H, Doi K. Malignant versus benign nodules at CT screening for lung cancer: comparison of thin-section CT findings. Radiology 2004;233:793-798
Hara M, Oda K, Ogino H, et al. Focal fibrosis as a cause of localized ground glass attenuation (GGA): CT and MR findings. Radiat Med 2002; 20:93-95
C. M. Park, J. M. Goo, H. J. Lee, C. H. Lee, E. J. Chun, and J.-G. Im Nodular Ground-Glass Opacity at Thin-Section CT: Histologic Correlation and Evaluation of Change at Follow-up RadioGraphics, March 1, 2007; 27(2): 391 – 408.
4.9 Hilar enlargement on prior imaging
4.10 Hyperaeration of lung field on prior imaging
4.11.1.1 Less than 6 mm, CT at 12 months and no further follow-up if unchanged
4.11.1.2 6 – 8 mm, CT at 6 – 12 months then CT at 18 – 24 months
4.11.1.3 Greater than 8 mm, consider CT at 3 months, PET/CT, or tissue sampling
4.11.2.1 Less than 6 mm, No routine follow-up
4.11.2.2 6 – 8 mm, CT at 6 – 12 months then consider CT at 18 – 24 months
4.11.2.3 Greater than 8 mm, consider CT at 3 months, PET/CT, or tissue sampling
4.11.3.1 Smoker, Asymptomatic, >35 YO (High Risk)
4.11.3.1.1 Less than 6 mm, CT at 12 months and no further follow-up if unchanged
4.11.3.1.2 6 – 8 mm, CT at 3 – 6 months then CT at 18 – 24 months
4.11.3.1.3 Greater than 8 mm, CT at 3 – 6 months then CT at 18 – 24 months
4.11.3.2.1 Less than 6 mm, No routine follow-up
4.11.3.2.2 6 – 8 mm, CT at 3 – 6 months then CT at 18 – 24 months
4.11.3.2.3 Greater than 8 mm, CT at 3 – 6 months then CT at 18 – 24 months
4.11.4 Nodule or nodules in patient <35 years of age, one low dose CT at 6-12 months
4.11.5 REFERENCE: MacMahon H, Naidich DP, Goo JM, et al. Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017. Radiology July 2017; 284 (1): 228-243.
https://pubs.rsna.org/doi/full/10.1148/radiol.2017161659
4.12.1 Age >35
4.12.2 Enlarged compared to prior exam
4.12.3 Age <35 with equivocal, eccentric or no calcifications on prior exam
4.12.4 Smoker
4.12.5 Known malignancy elsewhere
4.12.6 Abnormal findings at the lung base on recent CT of the abdomen
Helen T. Winer-Muram, The Solitary Pulmonary Nodule, Radiology 2006 239: 34-49.
MacMahon H, Austin JHM, Gamsu G, et al., Guidelines for management of small pulmonary nodultes detected on CT scans: A statement from the Fleischner Society, Radiology, 2005; 237:395 Henschke CI, Yankelevitz DF, Naidich DP, et al. CT screening for lung cancer: suspiciousness of nodules according to size on baseline scans. Radiology 2004;231(1):164-168
Clinical Significance of Small Pulmonary Nodules with Little or No 18F-FDG Uptake on PET/CT Images of Patients with Nonthoracic Malignancies Joo Hyun O, Ie Ryung Yoo, Sung Hoon Kim, Hyung Sun Sohn, and Soo Kyo Chung J Nucl Med 48: 15-21.Tissue Characterization of Solitary Pulmonary Nodule: Comparative Study Between Helical Dynamic CT and Integrated PET/CT Chin A Yi, Kyung Soo Lee, Byung-Tae Kim, Joon Young Choi, O. Jung Kwon, Hojoong Kim, Young Mog Shim, and Myung Jin Chung J Nucl Med 47: 443-450 Frank C. Detterbeck, Steven Falen, M. Patricia Rivera, Jan S. Halle, and Mark A. Socinski
Seeking a Home for a PET, Part 1 : Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses Chest June 2004 125:2294-2299 Frank C. Detterbeck, Steven Falen, M. Patricia Rivera, Jan S. Halle, and Mark A. Socinski Seeking a Home for a PET, Part 1 : Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses Chest June 2004 125:2294-2299
Keith Robert L, “Chapter 41. Bronchogenic Carcinoma & Solitary Pulmonary Nodules” (Chapter). Hanley ME, Welsh CH: CURRENT Diagnosis & Treatment in Pulmonary Medicine: http://www.accessmedicine.com/content.aspx?aID=578809.
4.13 Pleural fluid on prior imaging or physical examination
4.14.1 Asbestos exposure
McLoud, TC, Woods, BO, Carrington, CB, Epler, GR, Gaensler, EA Diffuse pleural thickening in an asbestos-exposed population: prevalence and causes Am. J. Roentgenol. 1985 144: 9-18 Henk Kramer, Remge M. Pieterman, Dirk-Jan Slebos, Wim Timens, Willem Vaalburg, Gerard H. Koëter, and Harry J.M. Groen PET for the Evaluation of Pleural Thickening Observed on CT J Nucl Med 45: 995-998. D R Warakaulle, and Z C Traill Imaging of pleural disease Imaging 16: 10-21, Kim, FM, Fennessy, JJ Pleural thickening caused by leukemic infiltration: CT findings Am. J. Roentgenol. 1994 162: 293-294
4.15.1.1 Bourke, S J; Interstitial lung disease: progress and problems; Postgrad Med J 2006 82: 494-499
4.15.1.2 Du Bois, R M Fortnightly Review: Diffuse lung disease: an approach to management BMJ 1994;309:175
4.16 Sputum Cytology suggest malignancy
5.1.1 Changed clinical situation
5.1.2 Interval follow up
Franziska Albrecht, Friedrich Eckstein, and Peter Matt Is close radiographic and clinical control after repair of acute type A aortic dissection really necessary for improved long-term survival? Interact CardioVasc Thorac Surg 2010;11:620-625;
5.2.1.1.1 Cervix Cancer
5.2.1.1.2 Colon Cancer
5.2.1.1.3 Hodgkin’s Disease
5.2.1.1.4 Lymphoma
5.2.1.1.5 Melanoma
5.2.1.1.6 Renal Cell Cancer
5.2.1.1.7 Sarcomas
5.2.1.1.8 Testicular or germ cell cancer
5.2.1.1.9 Thymoma
5.2.1.2.1 Cough
5.2.1.2.2 CTA of the chest is preferred
5.2.1.2.3 Dyspnea, acute onset
5.2.1.2.4 Hemoptysis
5.2.1.2.5 Known DVT by sonography
5.2.1.2.6 Known Malignancy
5.2.1.2.7 Pleuritic chest pain
5.2.1.2.8 Tachypnea
5.2.1.3 Suspected lesion on chest radiograph
5.2.2.1 Airway compromise
5.2.2.2 Chest pain
5.2.2.3 Deteriorating radiographic or clinical picture
5.2.2.4 Dysphagia
5.2.2.5 Hoarseness
5.2.2.6.1.1 NCCN Practice Guidelines in Oncology v.2.2009 Non small cell Lung Cancer p17 accessed 12/30/08
5.2.2.7 Syndrome of inappropriate ADH
5.2.3.1 Initial work up of invasive cancers
5.2.3.2 For ROUTINE follow up see oncology section
5.2.3.3.1 NCCN Clinical Practice Guidelines in Breast Cancer V.1.2010 accessed 03/15/10
5.2.4.1 Initial work up
NCCN Clinical Practice Guidelines in Oncology™ Cervical Cancer V.1.2007 p.5
Kavanagh John J, Phan Alexandria T, Tangjitgamol Siriwan, Ramirez Pedro T, “Chapter 24. Tumors of the Uterine Cervix” (Chapter). Kantarjian HM, Wolff RA, Koller CA: MD Anderson Manual of Medical Oncology: http://www.accessmedicine.com/content.aspx?aID=2795094
5.2.5.1 Initial work up
5.2.6.1 Initial evaluation
5.2.6.2 Following completion treatment
5.2.6.3.1 Cervical lymph node new or enlarging
5.2.6.3.2 Chest pain
5.2.6.3.3 Cough
5.2.6.3.4 Dysphagia
5.2.6.3.5 Dyspnea
NCCN Practice Guidelines in Oncology Esophageal Cancer v.1.2009 Tae Jung Kim, Kyoung Ho Lee, Young Hoon Kim, Sook Whan Sung, Sanghoon Jheon, Suk-ki Cho, and Kyung Won Lee Postoperative Imaging of Esophageal Cancer: What Chest Radiologists Need to Know RadioGraphics 2007 27: 409-429.
Yamabe, Yuichiro, Kuroki, Yoshifumi, Ishikawa, Tsutomu, Miyakawa, Kunihisa, Kuroki, Seiko, Sekiguchi, Ryuzo Tumor Staging of Advanced Esophageal Cancer: Combination of Double-Contrast Esophagography and Contrast-Enhanced CT Am. J. Roentgenol. 2008 191: 753-757
5.2.7.1 Initial work up, metastases suspected
5.2.7.2 Surveillance of asymptomatic patient at 6 month intervals
NCCN Clinical Practice Guidelines in OncologyHodkin Disease/LymphomaCancers V.2.2009 accessed 1/22/09 American College of Radiology ACR Appropriateness Criteria® Clinical Condition: Staging Evaluation-Hodgkin’s Lymphoma 2005
5.2.8.1.1.1 Abnormal CXR
5.2.8.1.1.2 Cough
5.2.8.1.1.3 Hemoptysis
5.2.8.1.1.4 Hoarseness
5.2.8.2 Stage III or IV CT or PET/CT may be approved
5.2.8.3.1 09NCCN Practice Guidelines in Oncology v.2.2009 Melanoma accessed 12/30
5.2.9.1 Initial work up, metastases suspected
5.2.9.2 Surveillance of asymptomatic patient at 6 month intervals
Lam, JS, Shvarts, O, Leppert, JT, et al. Postoperative surveillance protocol for patients with localized and locally advanced renal cell carcinoma based on a validated prognostic nomogram and risk group stratification system. J Urol 2005; 174:466
5.2.10.1 Initial work up, metastases suspected
5.2.10.2 Surveillance of asymptomatic patient at 3 – 6 month intervals
5.2.10.3.1 NCCN Clinical Practice Guidelines in Oncology™ Sarcoma V.2.2007
5.2.11.1 Initial workup
5.2.11.2 Restaging
NCCN Practice Guidelines in Oncology Testicular Cancer V2.2009 M. L. Harvey , T. R. Geldart , R. Duell , G. M. Mead , and K. Tung Routine computerised tomographic scans of the thorax in surveillance of stage I testicular non-seminomatous germ-cell cancer-a necessary risk? Ann Oncol 13: 237-242. [Paper indicates no real value from routine CT follow up, but increased risk of radiation induced malignancy.] Sohaib, S. Aslam, Koh, Dow-Mu, Husband, Janet E. The Role of Imaging in the Diagnosis, Staging, and Management of Testicular Cancer Am. J. Roentgenol. 2008 191: 387-395 [Takes a more favorable view of using chest CT. But recognizes the risk.]
5.3.1 Surveillance or change in clinical picture
5.3.2.1 “The disorder is one of several resulting from abnormalities in collagen and elastin. The fragile skin can be susceptible to bruising and poor healing of wounds, leaving ”cigarette paper“ scars ”
Lichtman’s Atlas of Hematology A. External Manifestations Marshall A. Lichtman, Jean A. Shafer, Raymond E. Felgar, Nancy Wang Copyright © 2007, by The McGraw-Hill Companies, Inc. Aneurysm formation is also characteristic
5.4.1 Change in clinical status
5.4.2 Interval follow up
Sabiston Textbook of Surgery, 17th Edition (2004) Townsend et al, eds; p 1909
Schwartz’s Principles of Surgery, 8th Edition F. Charles Brunicardi, Dana K. Andersen, Timothy R. Billiar, David L. Dunn, John G. Hunter, Jeffrey B. Matthews, Raphael E. Pollock, Seymour I. Schwartz Copyright © 2005, The McGraw-Hill Companies, Inc. Part II. Specific Considerations > Chapter 21. Thoracic Aortic Aneurysms and Aortic Dissection from www.accessmedicine.com/content.aspx?aID=805165 accessed 7/5/07
5.5 Mediastinal mass, known
5.6.1 Thymoma suspected
Drachman DB. Myasthenia gravis. N Engl J Med 1994;330:1797-1810
Thanvi, B R, Lo, T C N Update on myasthenia gravis Postgrad Med J 2004 80: 690-700
5.7.1 Recurrent in the same location
5.7.2 Unresponsive to treatment.
5.8.1 To evaluate extent of disease
5.8.2 Interval follow up (annual)
5.8.3 Worsening symptoms
Baughman RP, Lower EE. Chapter 329. Sarcoidosis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison’s Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012. http://www.accessmedicine.com/content.aspx?aID=9138725. Accessed October 18, 2012
Sarcoidosis: Clinical Presentation, Immunopathogenesis, and Therapeutics Michael C. Iannuzzi, Joseph R. Fontana JAMA. 2012;305(4):391-399.
Sarcoidosis: correlation of extent of disease at CT with clinical, functional, and radiographic findings. Müller NL, Mawson JB, Mathieson JR, Abboud R, Ostrow DN, Champion P Radiology. 1989;171(3):613.
Pulmonary sarcoidosis. Baughman RP Clin Chest Med. 2004;25(3):521
Radiologic manifestations of sarcoidosis in various organs. Koyama T, Ueda H, Togashi K, Umeoka S, Kataoka M, Nagai S Radiographics. 2004;24(1):87.
5.9.1.1 History of at least 30 pack years (daily number of packs smoked multiplied by the number of years smoked)
5.9.1.2 Currently smoking, or smoked within the last 15 years
5.9.1.3 Aged between 55 and 80 years
Draft Recommendation Statement USPTF Accesses 10/28/2013 at http://www.uspreventiveservicestaskforce.org/uspstf13/lungcan/lungcandraftrec.htm
5.10 Thymoma, Known
Robert G. Hayter, James T. Rhea, Andrew Small, Faranak S. Tafazoli, and Robert A. Novelline Suspected Aortic Dissection and Other Aortic Disorders: Multi-Detector Row CT in 373 Cases in the Emergency Setting Radiology 2006 238: 841-852
Louise A. Prince, Gary A. Johnson in Tintinalli’s Emergency Medicine:A Comprehensive Study Guide, 6th Edition Judith E. Tintinalli, MD, MS, Gabor D. Kelen, MD, J. Stephan Stapczynski, MD, O. John Ma, MD and David M. Cline, MD Eds. The American College of Emergency Physicians> Section 7: Cardiovascular Disease > Chapter 58. Aortic Dissection and Aneurysms
Sabiston Textbook of Surgery, 17th Edition (2004) Townsend et al, eds; pp1907 – 1913