1 Vertebral fracture with suspected bone metastasis

2 Suspected Multiple Myeloma

3 Known hematologic malignancies (leukemia, lymphoma, multiple myeloma, other blood cancers):

  • 3.1 Staging
  • 3.2 Monitoring treatment response

4 Suspected metastatic bone disease

5 Suspected or known bone marrow disorders

  • 5.1 Chronic recurrent multifocal osteomyelitis
  • 5.2 Gaucher’s disease
  • 5.3 Waldenstrom macroglobulinemia

6 Evaluate bone pain

7 Spinal cord compression

8 Evaluate bone marrow edema

9 Evaluate high-risk monoclonal gammopathy of undetermined significance (MGUS)

References

  • Baur-Melnyk, A., Buhmann, S., Durr, H.R., & Reiser, M. (2005). Role of MRI for the diagnosis and prognosis of multiple myeloma. European Journal of Radiology, 55(1), 56- 63. doi:10.1016/j.ejrad.2005.01.017.
  • Schmidt, G.P., Schoenberg, S.O., Reiser, M.F., & Baur-Melnyk, A. (2005). Whole-body MR imaging of bone marrow. European Journal of Radiology, 55(1), 33-40. doi: 10.1016/j.ejrad.2005.01.019.
  • Grønningsæter IS et al. “Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies”. Clin Pract. 2018 Jun 7;8(2):1061. https://pmc.ncbi.nlm.nih.gov/articles/PMC6047479/
  • Moulopoulos LA, Dimopoulos MA. “Magnetic Resonance Imaging of the Bone Marrow in Hematologic Malignancies”. Blood. 1997. 90 (6):2127-2147. https://pubmed.ncbi.nlm.nih.gov/9310464/
  • Mourad C et al. “Advances in Bone Marrow Imaging: Strengths and Limitations from a Clinical Perspective”. Semin Musculoskelet Radiol. 2023 Feb;27(1):3-21. https://pmc.ncbi.nlm.nih.gov/articles/PMC9984270/