1 Dementia

  • 1.1 Agnosia
  • 1.2 Aphasia
  • 1.3 Apraxia
  • 1.4 Confusion
  • 1.5 Disorientation
  • 1.6 Fluctuating cognition
  • 1.7 Memory loss
  • 1.8 Mini Mental State score of 24 or less on two occasions
  • 1.9 Recurrent visual hallucinations
  • 1.10 spontaneous motor features of Parkinsonism

2 Epilepsy to localize a focus preparatory to corrective surgery

References

  • Daniel H.S. Silverman Brain 18F-FDG PET in the Diagnosis of Neurodegenerative Dementias: Comparison with Perfusion SPECT and with Clinical Evaluations Lacking Nuclear Imaging J Nucl Med 45: 594-607. Ana M. Catafau Brain SPECT in Clinical Practice. Part I: Perfusion J Nucl Med 42: 259-271.
  • McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathological diagnoses of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. Neurology. 1996;47:1113–1124 AD Murray Imaging in dementia Imaging 19: 133-141, 2007 Seok Ming Lim, et al The 18F-FDG PET Cingulate Island Sign and Comparison to 123I-β-CIT SPECT for Diagnosis of Dementia with Lewy Bodies J Nucl Med 50: 1638-1645; First published on September 16, 2009

3 Parkinson’s disease and syndromes- Atypical presentation

4 Immunocompromised patients with mass lesion detected on CT or MR for differentiation of lymphoma and infection

References

  • Desai A1, Bekelis K, Thadani VM, Roberts DW, Jobst BC, Duhaime AC, Gilbert K, Darcey TM, Studholme C, Siegel A. Interictal PET and ictal subtraction SPECT: sensitivity in the detection of seizure foci in patients with medically intractable epilepsy. Epilepsia. 2013 Feb;54(2):341-50. doi: 10.1111/j.1528-1167.2012.03686.x. Epub 2012 Oct 2.
  • Raúl de la Fuente-Fernández, MD Role of DaTSCAN and clinical diagnosis in Parkinson disease Neurology March 6, 2012 vol. 78 no. 10 696-701 American College of Radiology Appropriateness http://www.acr.org/~/media/ACR/Documents/AppCriteria/Diagnostic/DementiaAndMovementDisorders
  • Lorberboym M1, Estok L, Machac J, Germano I, Sacher M, Feldman R, Wallach F, Dorfman D. Rapid differential diagnosis of cerebral toxoplasmosis and primary central nervous system lymphoma by thallium-201 SPECT. J Nucl Med. 1996 Jul;37(7):1150-4.

References

  • Daniel H.S. Silverman Brain 18F-FDG PET in the Diagnosis of Neurodegenerative Dementias: Comparison with Perfusion SPECT and with Clinical Evaluations Lacking Nuclear Imaging J Nucl Med 45: 594-607. Ana M. Catafau Brain SPECT in Clinical Practice. Part I: Perfusion J Nucl Med 42: 259-271.
  • Desai A1, Bekelis K, Thadani VM, Roberts DW, Jobst BC, Duhaime AC, Gilbert K, Darcey TM, Studholme C, Siegel A. Interictal PET and ictal subtraction SPECT: sensitivity in the detection of seizure foci in patients with medically intractable epilepsy. Epilepsia. 2013 Feb;54(2):341-50. doi: 10.1111/j.1528-1167.2012.03686.x. Epub 2012 Oct 2.
  • Raúl de la Fuente-Fernández, MD Role of DaTSCAN and clinical diagnosis in Parkinson disease Neurology March 6, 2012 vol. 78 no. 10 696-701 American College of Radiology Appropriateness http://www.acr.org/~/media/ACR/Documents/AppCriteria/Diagnostic/DementiaAndMovementDisorders