MUGA (Multigated Radionuclide Angiography: 78472, 78473, 78481, 78483, 78494, 78496 – Care to Care's Clinical Criteria

Note: These studies all measure ejection fraction, a measure of cardiac function. Similar data is available from SPECT myocardial perfusion imaging, and if such a study has been performed within a 10 days of a request for one of these examinations the request should be referred for physician review.

Congestive Heart Failure

New onset

Change of clinical statusa

Prior to or during the administration of potentially cardiotoxic chemotherapy

Gavin I.W. Galasko and Avijit Lahiri The non-invasive assessment of hibernating myocardium in ischaemic cardiomyopathy—a myriad of techniques. Eur J Heart Fail (2003) 5(3): 217-227.

CMS Medicare coverage: http://www.cms.gov/medicare-coverage-database/details/ncddetails.aspx?NCDId=298&ncdver=1&SearchType=Advanced&CoverageSelection=National&NCSelection=NCD&KeyWord=Myocardial&KeyWordLookUp=Title&KeyWordSearchType=Exact&kq=true&bc=IAAAABAAAAAAAA%3d%3d&

Hendel RC, et al. ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 Appropriate Use Criteria for Cardiac Radionuclide Imaging, J Am Coll Cardiol, 2009; 53:2201-29.

Clinical pharmacology: Cardiotoxic drugs: clinical monitoring and decision making Audrey H Wu Heart 2008;94:1503-1509 doi:10.1136/hrt.2007.133876

Kremer, LC, Caron, HN. Anthracycline cardiotoxicity in children. N Engl J Med 2004; 351:120.

Alterations in left ventricular diastolic function with doxorubicin therapy. Lee BH; Goodenday LS; Muswick GJ; Yasnoff WA; Leighton RF; Skeel RT J Am Coll Cardiol 1987 Jan;9(1):184-8.